Neuromuscular Transmission Involves the Sequential Activation of Several Ion Channels

question 35

Short Answer

Neuromuscular transmission involves the sequential activation of several ion channels. Sort the following events to reflect the sequence leading to muscle contraction. Your answer would be a five-digit number composed of numbers 1 to 5 only, e.g. 12543.
(A) Opening of voltage-gated Na? channels in the muscle cell plasma membrane.
(B) Opening of Ca²⁺ release channels in the sarcoplasmic reticulum membrane.
(C) Opening of ionotropic acetylcholine receptors on the muscle cell plasma membrane.
(D) Opening of voltage-gated Ca²⁺channels in the T tubules.
(E) Opening of voltage-gated Ca²⁺channels in the motor neuron.

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