Consider a Transmembrane Protein with the Following Topology That Has

question 39

Multiple Choice

Consider a transmembrane protein with the following topology that has an internal signal sequence (helix 1) . If you fuse a canonical ER signal sequence at the N-terminus of this protein, how would you expect the topology to change? The ER lumen is at the bottom in all drawings. For simplicity, assume that the effect of charged residues flanking the transmembrane helices is negligible in this case.

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Definitions:

Behaviour

The manner in which an individual or group acts or conducts themselves, especially towards others.

Members

Individuals who are part of a group, organization, or community and often share common interests or goals.

Team Productivity

The efficiency and effectiveness with which a group of individuals work together to achieve common goals, often measured by output or results.

Team Cohesiveness

The extent to which team members stick together and remain united in their pursuit of common goals.