A Protein Is Covalently Attached to Glycosylphosphatidylinositol

question 14

Multiple Choice

A protein is covalently attached to glycosylphosphatidylinositol. Which of the following is typically NOT true regarding this protein?

• A) The linkage of the anchor to the C-terminus of the protein occurs in the ER.
• B) The attachment of the anchor coincides with cleavage of a C-terminal transmembrane segment of the protein precursor.
• C) The protein is likely to be an ER resident, helping with the folding of nascent imported proteins.
• D) A phospholipase can cleave the protein from the membrane.
• E) The anchor affects the localization of the protein in the membrane.

---

Definitions:

Concrete

A building material made from a mixture of broken stone or gravel, sand, cement, and water, which can be spread or poured into molds and forms a stone-like mass on hardening.

Abstract

Referring to concepts or ideas that are not concrete or tangible, but are instead thought of in a theoretical or conceptual way.

Chopsticks

Eating utensils consisting of a pair of long, thin pieces of wood or other material, commonly used in many East Asian countries.

Ought-Actual Discrepancy

The gap between how individuals believe they should be (ought self) and how they actually perceive themselves (actual self), potentially leading to stress or discomfort.