A Certain Effector Protein Can Be Activated by Phosphorylation at a Key

question 50

Short Answer

A certain effector protein can be activated by phosphorylation at a key tyrosine residue. An upstream kinase rapidly phosphorylates this tyrosine in the presence of a signal. However, the kinase also phosphorylates and activates a slow-acting phosphatase that can dephosphorylate the phosphotyrosine. Which curve in the following graph would you expect to represent the activity of the effector molecule over time? The input signal is present during the period indicated in gray. The dashed line represents the response in the absence of the phosphatase.

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