Whereas the Cholera Toxin ADP-Ribosylates the α Subunit of Stimulatory

question 16

Multiple Choice

Whereas the cholera toxin ADP-ribosylates the α subunit of stimulatory G protein (Gs) , thereby blocking GTP hydrolysis, pertussis toxin ADP-ribosylates the α subunit of inhibitory G protein (Gᵢ) and prevents interaction with the receptor. What is the effect of these toxins on the concentration of intracellular cAMP?

• A) Cholera toxin tends to increase cAMP concentration, whereas pertussis toxin tends to decrease cAMP concentration.
• B) Cholera toxin tends to decrease cAMP concentration, whereas pertussis toxin tends to increase cAMP concentration.
• C) They both tend to increase cAMP concentration.
• D) They both tend to decrease cAMP concentration.

---

Definitions:

Cost Effective

A term that describes a process, project, or expenditure that provides the best possible outcome or value for the money spent.

Training Needs

Identifications of gaps in skills, knowledge, and abilities among employees, determining what training is required to bridge these gaps for improved performance.

Double-Loop Learning

A learning concept where individuals not only make corrections based on mistakes but also examine and adapt the underlying governing values and policies.

Setbacks

Unforeseen challenges or obstacles that hinder progress or achievement of goals.