In the Following Diagram Showing Five Parallel Signaling Pathways Downstream

question 18

Short Answer

In the following diagram showing five parallel signaling pathways downstream of a receptor tyrosine kinase (RTK) and a G-protein-coupled receptor (GPCR), indicate which boxes (A to E) correspond to the following proteins. Your answer would be a five-letter string composed of letters A to E only, e.g. CDBAE.

( ) Cyclic AMP
( ) Protein kinase C
( ) Sos
( ) PI(3,4,5)P₃
( ) Ca²⁺

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Definitions:

Melanoma

A type of skin cancer that develops from the pigment-producing cells known as melanocytes.

Eczema

A condition that causes inflamed, itchy, cracked, and rough skin.

Scabies

A contagious skin infestation caused by the mite Sarcoptes scabiei, characterized by intense itching and a rash.

Basal Cell Carcinoma

A type of skin cancer originating in the basal cells, which are located in the deepest layer of the epidermis, and is characterized by its slow growth.