You Have Synchronized a Culture of HeLa Cells So That

question 30

Multiple Choice

You have synchronized a culture of HeLa cells so that the cells are all at the same stage in the cell cycle. You then treat the cells with serum containing nutrients and growth factors in the presence or absence of the drug rapamycin. The distribution of cell sizes in the two cell populations is shown below. Based on these results, do you think rapamycin is an activator or inhibitor of the TOR complex? Is the S6 kinase expected to be up-regulated or down-regulated in the presence of rapamycin?

• A) Activator; up-regulated
• B) Activator; down-regulated
• C) Inhibitor; up-regulated
• D) Inhibitor; down-regulated Answers

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Definitions:

Correlation

A statistical measure that describes the extent to which two variables change together, but does not necessarily imply causation.

Causation

The relationship between cause and effect where one event (the cause) makes another event happen (the effect).

Usage Tax

Usage tax is a levy on the use of goods or services, typically calculated as a percentage of the purchasing price or a flat rate, aimed at specific products or activities.

Difference-In-Differences

is an econometric technique used to estimate the effect of a specific intervention or treatment by comparing the changes in outcomes over time between a treatment group and a control group.