Apoptotic Cells Are Efficiently Phagocytosed by Neighboring Cells or Macrophages

question 8

Multiple Choice

Apoptotic cells are efficiently phagocytosed by neighboring cells or macrophages. Which of the following DOES NOT normally happen in this process?

• A) The apoptotic cell releases some of its cytoplasmic content to induce a local inflammatory response.
• B) The apoptotic cell exposes phosphatidylserine at its surface, which interacts with receptor proteins on the surface of phagocytes via "bridging" proteins.
• C) The apoptotic cell loses or inactivates "don't eat me" signals.
• D) The apoptotic cell rounds up and detaches from its neighbors, which facilitates phagocytosis.

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