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EDTA Is a Metal-Ion "Chelator" That Is Commonly Used to Lower

question 46

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EDTA is a metal-ion "chelator" that is commonly used to lower the concentration of free divalent cations in solution. In the lab, your friend has cultured a human cell line on elastic membranes that have been coated with fibronectin and attached to a device that can stretch the membrane. She has quantified the binding of talin to integrin under different conditions, and has presented the results in the following schematic graph, which shows the binding in the presence or absence of EDTA in the cell-culture medium. Which experiment (A or B) do you think was performed in the presence of EDTA? Write down A or B as your answer. EDTA is a metal-ion  chelator  that is commonly used to lower the concentration of free divalent cations in solution. In the lab, your friend has cultured a human cell line on elastic membranes that have been coated with fibronectin and attached to a device that can stretch the membrane. She has quantified the binding of talin to integrin under different conditions, and has presented the results in the following schematic graph, which shows the binding in the presence or absence of EDTA in the cell-culture medium. Which experiment (A or B) do you think was performed in the presence of EDTA? Write down A or B as your answer.


Definitions:

Correlational Coefficient

A statistical measure that indicates the extent to which two or more variables fluctuate together, showing the direction and strength of a relationship between variables.

Error

A mistake made in thinking or action that leads to incorrect or unintended results.

Negative Correlation

A relationship between two variables in which one variable increases as the other decreases, indicating an inverse association.

Variable Increases

Situations or conditions where a measurable factor or quantity grows in magnitude or intensity.

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