You Have Analyzed a Large Set of Human Cancer-Critical Genes

question 33

Multiple Choice

You have analyzed a large set of human cancer-critical genes for a selected group of carcinomas, classifying each of the genes based on whether they are known to undergo somatic or germ-line mutations, as well as based on whether they are dominant or recessive. You then group them and plot the statistics in the following histograms. Which group (a or b) do you think represents somatic, as compared to germ-line, mutations? Which group (1 or 2) do you think represents dominant, as compared to recessive, mutations? (Note that the sum of percentages of somatic and germ-line mutations is more than 100%, since some genes are mutated in both somatic and germ cells) .

• A) a; 1
• B) a; 2
• C) b; 1
• D) b; 2

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Definitions:

Negotiating within Relationships

The practice of negotiation that takes into account the long-term relationship between the parties involved.

Parameters

The boundaries, rules, or limits that define the scope of a particular process or activity.

Laboratory Controlled Research

Laboratory controlled research refers to studies conducted in a strictly controlled environment, often within a lab, to isolate variables and determine causality.

Field Research

Empirical research conducted in real-world settings outside the laboratory to gather data directly from a natural environment.