Genetically Knocking Out Both Copies of the P53 Gene in Rats

question 31

Multiple Choice

Genetically knocking out both copies of the p53 gene in rats …

• A) is embryonic lethal.
• B) results in a lower malignancy rate, but the rats are otherwise seemingly normal.
• C) results in a higher rate of cancer onset, but the rats are otherwise seemingly normal.
• D) increases cell death by apoptosis, leading to developmental defects.
• E) does not have any effect unless the rats live outside of the laboratory and are exposed to various types of stress.

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Definitions:

Tachy-

A prefix used in medical terms to denote rapid or accelerated, often referring to the rate of a heartbeat.

Megalo-

A prefix used in medical terms to denote something that is abnormally large or elongated.

Pan-

A prefix meaning "all" or "every," indicating inclusiveness or a broad scope, as in "pan-African" or "panacea."

Iasis

Refers to a condition or disease state, often used as a suffix in medical terms.