Consider Agrin Signaling in the Formation of Neuromuscular Junctions in Vertebrates

question 56

Short Answer

Consider Agrin signaling in the formation of neuromuscular junctions in vertebrates. Shp2 is a protein tyrosine phosphatase that counteracts the tyrosine kinase activity of MuSK. Rapsyn interacts with the acetylcholine receptors and induces their agrin-dependent clustering. Indicate whether each of the following is expected to enhance (E) or suppress (S) acetylcholine receptor clustering in this process. Your answer would be a four-letter string composed of letters E and S only, e.g. EEEE.
( ) Specific inhibition of Shp2
( ) Loss of Rapsyn
( ) Loss of LRP4
( ) Constitutive activation of MuSK

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Definitions:

Normal Production

The average production capacity or level of output that a manufacturing process or plant is designed to achieve under normal conditions.

Direct Material Quantity Variance

The variance between the real amount of materials consumed in production and the anticipated standard quantity, multiplied by the cost per unit set by standards.

Actual Production

The total amount of output that a company has produced within a specific period.

Normal Production

Normal Production refers to the average amount of goods or services produced during a specific period under typical operating conditions.