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In Some Adenomas of the Colon, Intestinal Crypt Cells Appear

question 13

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In some adenomas of the colon, intestinal crypt cells appear to have proliferated abnormally to form small tumors known as polyps. Studies on the familial type of such a disease led to the identification of a major signaling pathway (which was aberrant in the polyp cells) as being involved in the maintenance of the gut stem-cell compartment. What signaling pathway is this? Is it upregulated or downregulated in colon cancers?


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Thoughts or concepts that are composed of multiple elements, requiring significant thought or abstraction to understand.

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Cost per thousand impressions, a common metric used in advertising to denote the cost of 1,000 advertisement impressions on one webpage.

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