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In Some Adenomas of the Colon, Intestinal Crypt Cells Appear

question 13

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In some adenomas of the colon, intestinal crypt cells appear to have proliferated abnormally to form small tumors known as polyps. Studies on the familial type of such a disease led to the identification of a major signaling pathway (which was aberrant in the polyp cells) as being involved in the maintenance of the gut stem-cell compartment. What signaling pathway is this? Is it upregulated or downregulated in colon cancers?


Definitions:

Ethernet Cable

A type of network cable used for wired networks to connect devices such as computers, routers, and switches.

Modem

A hardware device that converts data between digital formats used by computers and analog signals used on telephone lines, enabling internet connectivity.

Network

A system of interconnected computers, devices, and technologies designed to communicate and exchange data.

Hub

A central point of connection in a network that redistributes data to various destinations.

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