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Tolerance
The capacity to endure continued exposure to a substance or activity without adverse reaction, often leading to the need for increased amounts to achieve the same effect.
Physical Dependence
A physiological state of adaptation to a substance, resulting in withdrawal symptoms when that substance is reduced or stopped.
Nucleus Accumbens
A region in the brain involved in the reward circuit, associated with pleasure, reinforcement learning, addiction, and fear.
Reward Pathway
A neural pathway in the brain that is activated by rewarding stimuli, playing a critical role in the reinforcement and motivation processes.
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