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Exhibit 6A This is a reaction going on in your muscle cells right this very minute: The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics:
Typical cellular concentrations: triose phosphate isomerase = 0.1 nM
Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM
Refer to Exhibit 6A. "Restrainin" is an inhibitor of triose phosphate isomerase. When it is added to cells at a concentration of 0.4 nM, the enzyme's apparent KM for the substrate is altered to 100 µM, but the Vmax is unchanged.
Irving Gottesman
A psychologist known for his work on schizophrenia genetics, demonstrating the importance of heredity in the development of the disorder.
Schizophrenia
A serious mental illness marked by altered cognition, perceptions, feelings, speech, self-awareness, and actions.
Monozygotic Twins
Identical twins that result from a single fertilized egg splitting and developing into two individuals with virtually identical genetic makeup.
Biological Parents
The parents who contributed their genetic material to the birth of a child.
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