How Do Uncoupling Agents Affect the Electron Transport Chain and Oxidative

question 16

Multiple Choice

How do uncoupling agents affect the electron transport chain and oxidative phosphorylation?

• A) They block the flow of electrons, so protons aren't pumped, and ATP synthesis ceases.
• B) They remove electrons from the chain, so less protons are pumped, and ATP synthesis decreases.
• C) They block the flow of protons through the ATP synthase, so ATP synthesis ceases. Electron flow and proton pumping are also halted as a result.
• D) They provide an alternative path for protons to re-enter the mitochondrial matrix, so ATP synthesis decreases. Electron flow and proton pumping are not affected.