A Single Nucleotide Substitution Within a Gene Is Associated with Type

question 85

Essay

A single nucleotide substitution within a gene is associated with type 1 diabetes and a decrease in insulin secretion. What type of mutation is this? What type of protein (ion channel, hormone, peptide/hormone channel, peptide/hormone pump) is affected?

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Definitions:

Essential Elements

Fundamental components or factors that are necessary to form or define a particular entity or concept.

CISG

The United Nations Convention on Contracts for the International Sale of Goods, a set of rules governing the sale of goods between parties from different countries.

International Sales

The sale of goods or services across national boundaries, governed by international commercial law and trade agreements.

Void Contract

An agreement that is null and lacks legal effect or enforceability from its inception.