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Most Cancers Require at Least Two Mutations: 1) One in an Oncogene

question 12

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Most cancers require at least two mutations: 1) one in an oncogene, which encodes proteins that trigger cell division, and 2) one in a tumor suppressor gene, whose protein products, in their unmutated form, play a key role in preventing the cell cycle from progressing if the DNA is damaged or in the absence of specific cues. Which class of proteins might be considered tumor suppressors?


Definitions:

Foraging Time

The period spent by an animal searching for and gathering food.

Territoriality

Behavior in animals that involves the establishment and defense of a territory to claim exclusive use and resources.

Dominance

An attribute of an allele that masks the effect of a recessive allele paired with it in the phenotype of the organism.

Sexual Behavior

Actions related to how organisms reproduce, often influenced by biological, psychological, and social factors.

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