Narrative: Achondroplasia, a Hereditary Form of Dwarfism, Is an Autosomal Dominant

question 42

Multiple Choice

Narrative:
Achondroplasia, a hereditary form of dwarfism, is an autosomal dominant disorder; however homozygous dominant individuals either die before birth or very shortly thereafter. The homozygous recessive condition is normal. A dwarf couple decide to have children. Use this information to answer the following question:
Of the children of this couple who survive, what is probability that they will be affected by achondroplasia?

• A) 0
• B) ¼
• C) 1/3
• D) 2/3
• E) ½

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Definitions:

Self-Esteem

The subjective evaluation or personal view of one's own worth or importance.

Middle Childhood

A developmental stage that generally includes children from about six to twelve years of age, characterized by significant growth in cognitive and social abilities.

Differentiated

The process by which something becomes more specialized or distinct in its characteristics or functions.

Middle-Aged Workers

Individuals in the workforce typically ranging from about 40 to 65 years of age, often facing unique career and life stage challenges.