Why Is DNA Ligase Most Active on the Lagging Strand

question 75

Multiple Choice

Why is DNA ligase most active on the lagging strand during DNA replication?

• A) The lagging strands contain more short DNA segments, which are joined together by DNA ligase, than the leading strand.
• B) The lagging strand is synthesized more slowly, and DNA ligase speeds up the DNA polymerase.
• C) The lagging strand synthesizes DNA in the 3' ->5' direction.
• D) The lagging strand requires DNA ligase to couple the RNA primer to the Okazaki fragments.
• E) DNA ligase performs the function of RNA primase on the lagging strand.

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