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A 32-Year-Old Man Is Diagnosed with Major Depressive Disorder and Started

question 187

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A 32-year-old man is diagnosed with major depressive disorder and started on the selective serotonin reuptake inhibitor sertraline.  At his 2-week follow-up, the patient reports that his mood is "about the same."  He continues to feel sad and unmotivated most days and is short-tempered with his wife and kids.  He has little interest in food, sleeps poorly, and struggles to stay focused at work.  In the first 2-3 days of taking the medication, the patient experienced some mild nausea and anxiety that has since resolved.  He is now tolerating the medication without difficulty but is considering stopping it because he is discouraged by the lack of clear improvement.  Which of the following is the most likely explanation for this patient's lack of response?


Definitions:

Recurring Patterns

Regularly observed behaviors or occurrences that repeat over time in a predictable manner.

Individual Contributions

Refers to the specific inputs or efforts provided by individuals towards a common goal or project.

Overall System

refers to the entire set of components or elements that work together within a framework or environment.

Emotional Reaction

The immediate response of a person's feelings towards an event, situation, or experience.

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