As Part of a Research Study Investigating Enzymatic Activity in Both

question 21

Multiple Choice

As part of a research study investigating enzymatic activity in both normal and diseased liver tissue, hepatocytes are isolated from biopsy samples obtained from patients undergoing routine care at a local tertiary referral center.  The cells are homogenized and centrifuged to remove membrane components and organelles.  Following subsequent rounds of centrifugation, the remaining supernatant contains only cytosol and cytosolic proteins.  Activity of which of the following enzymes will most likely be detectable in the supernatant of healthy liver cells?

• A)3-Hydroxy-3-methylglutaryl-CoA lyase
• B)Ornithine transcarbamylase
• C)Pyruvate carboxylase
• D)Succinate dehydrogenase
• E)Transketolase

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Definitions:

Peripheral Nervous System

The Peripheral Nervous System consists of the nerves and ganglia outside of the brain and spinal cord, involved in transmitting information to and from the central nervous system.

Central Nervous System

The Central Nervous System consists of the brain and spinal cord, serving as the primary processing center for the entire nervous system.

Dendrites

Branch-like extensions of a neuron that receive signals from other nerve cells and are key players in neural communication.

Neuron

Morphologic and functional unit of the nervous system, consisting of the nerve cell body, the dendrites, and the axon; also called nerve cell.