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A 22-year-old man comes to the office due to recurrent blistering on the back of his hands and forearms for the past several years. The patient usually develops small itchy spots but lately has had large blisters that heal with hyperpigmentation after rupturing. He has used over-the-counter topical hydrocortisone and emollients, but the symptoms have not improved. The patient works as a night security guard and has had no exposure to chemicals or animals. He drinks 2-3 cans of beer daily. Physical examination shows vesicles and erosions on the dorsum of both hands. Which of the following enzymes is most likely deficient in this patient?
Euglenids
Unicellular organisms that are mostly autotrophic, belonging to the kingdom Protista.
Dinoflagellates
A group of single-celled organisms found in marine and freshwater environments, known for their role in algal blooms and as a food source in aquatic food chains.
Supergroup
Systematic term used to classify the major groups of eukaryotes based on DNA similarities.
Archaeplastids
Archaeplastids are a major group of eukaryotes that include plants and some algae, characterized by the presence of plastids with a double membrane.
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