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Researchers are interested in the association between colorectal carcinoma and nonsteroidal anti-inflammatory drug use. They first interview a group of patients with biopsy-proven colorectal carcinoma and then interview a group consisting of the patients' neighbors who are of similar age and race. The analysis is based on comparing the results of pairs of individuals (one from each of the 2 groups) who have similar characteristics. This design technique best helps address which of the following potential problems with this study?
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