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A New Tumor Marker Is Being Investigated for Its Usefulness

question 51

Multiple Choice

A new tumor marker is being investigated for its usefulness in diagnosing ovarian cancer.  A sample of 400 women is stratified into 2 groups based on the presence or absence of BRCA mutations.  Serum levels of the new marker are obtained in the 2 groups; in addition, both groups of women undergo conventional screening to determine their disease status.  The curves on the top represent the distribution of the new serum marker in women with BRCA mutations, and the curves on the bottom represent the distribution of the new serum marker in women without the BRCA mutations. A new tumor marker is being investigated for its usefulness in diagnosing ovarian cancer.  A sample of 400 women is stratified into 2 groups based on the presence or absence of BRCA mutations.  Serum levels of the new marker are obtained in the 2 groups; in addition, both groups of women undergo conventional screening to determine their disease status.  The curves on the top represent the distribution of the new serum marker in women with BRCA mutations, and the curves on the bottom represent the distribution of the new serum marker in women without the BRCA mutations.   The proposed serum marker cutoff value for both populations is shown.  Use of the new serum marker in women with BRCA mutations, compared with those without BRCA mutations, is associated with which of the following? A) Higher sensitivity and higher specificity B) Higher sensitivity and lower specificity C) Higher sensitivity and same specificity D) Lower sensitivity and higher specificity E) Lower sensitivity and lower specificity F) Lower sensitivity and unchanged specificity G) Unchanged sensitivity and unchanged specificity The proposed serum marker cutoff value for both populations is shown.  Use of the new serum marker in women with BRCA mutations, compared with those without BRCA mutations, is associated with which of the following?

Grasp the concept of morphemes as the smallest unit of meaning in language.
Understand the various stages and types of speech including telegraphic speech, overextension, and holophrases.
Identify the impact of adults' responses on children's language development, including pronunciation correction.
Recognize the importance of mean length of utterance (MLU) in language development and its associated researchers.

Definitions:

Investment Spending

Expenditures made for the purpose of acquiring new assets or upgrading existing ones to increase future productivity or revenue.

Transfer Payment

A payment of money (or goods and services) by a government to a household or firm for which the payer receives no good or service directly in return.

Subsidies

Financial support extended to an economic sector (or institution, business, or individual) with the aim of promoting economic and social policy objectives.

Wage Payments

The act of providing remuneration to employees for their labor, usually in the form of a monetary payment over a specified time period.

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