A Study Is Performed to Compare the Effect of Tramadol

question 42

Multiple Choice

A study is performed to compare the effect of tramadol when compared to placebo for painful polyneuropathy.  Fifty patients are selected and randomly allocated to 1 of 2 treatment sequences:  Tramadol followed by placebo, or placebo followed by tramadol.  The initial treatment period is delivered for 4 weeks followed by an interim 1-week washout phase, after which the second treatment period is delivered for an additional 4 weeks.  After each treatment period, patients use a 10-point numeric scale to rate pain, paresthesia, and tenderness.  Which of the following best describes this study design?

• A)Case-control study
• B)Case series study
• C)Crossover study
• D)Cross-sectional study
• E)Prospective cohort study
• F)Retrospective cohort study

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