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A 3-Year-Old Boy Is Being Evaluated for Recurrent Respiratory Infections

question 71

Multiple Choice

A 3-year-old boy is being evaluated for recurrent respiratory infections. The patient's family immigrated to the United States 5 months after his birth. Since then, the boy has experienced multiple episodes of pneumonia and bronchitis, and has developed a persistent cough and failure to thrive. His older brother has no medical issues. A genetic test is performed and reveals a mutation in an exon of a gene that codes for a transmembrane chloride channel. The abnormal mRNA is isolated from cultured epithelial cells, and its complementary DNA is synthesized. Amplified cDNA samples from both the patient and his healthy sibling are analyzed using gel electrophoresis and compared to DNA fragments of known size to determine base pair length. The results are shown below. Which of the following is most likely responsible for this patient's condition?

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The full range of features or operations that a system, device, or application is designed to perform.

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Solid State Drives; a type of non-volatile storage media that stores data on flash memory and has no moving parts, offering faster access and lower latency.

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The state of things as they actually exist, as opposed to an idealistic or notional idea of them.

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