A 68-Year-Old Man Comes to the Office for a Follow-Up

question 42

Multiple Choice

A 68-year-old man comes to the office for a follow-up appointment.  He has a history of advanced melanoma that is unresectable and resistant to adjuvant regimens.  The patient recently began receiving monoclonal antibody infusions for advanced melanoma.  The monoclonal antibodies block a specific cell surface receptor found on T lymphocytes.  As a result, T cells capable of recognizing tumor antigens have improved ability to destroy cancer cells.  Which of the following cell surface receptors is most likely blocked by the treatment?

• A)CCR5
• B)CD4
• C)CD19
• D)CD28
• E)PD-1

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Definitions:

Stethoscope

A medical device used for listening to the internal sounds of the body, such as the heartbeat and lung sounds, crucial for diagnosing many health conditions.

Postnasal Drip

A condition involving the excessive accumulation of mucus in the back of the throat or nose.

Night Cough

A cough that occurs or worsens during the night, potentially disrupting sleep and may indicate an underlying health issue.

Sinusitis

Inflammation of the sinuses, typically causing symptoms like headache, facial pain, and nasal congestion.