A 43-Year-Old Man Comes to the Emergency Department Due to 2

question 142

Multiple Choice

A 43-year-old man comes to the emergency department due to 2 weeks of intermittent fevers, malaise, and headaches.  He has a history of HIV and has not been taking his antiretroviral drugs recently.  Five years ago, the patient spent a year in jail.  Temperature is 38.2 C (100.8 F) .  Cerebrospinal fluid (CSF) analysis shows markedly elevated protein and low glucose, and CSF cultures grow Mycobacterium tuberculosis.  Resistance testing shows the following: Which of the following best explains the resistance pattern seen in these bacteria?

• A)Altered structure of bacterial ribosomal proteins
• B)Altered structure of enzymes involved in DNA winding-unwinding
• C)Altered structure of enzymes involved in RNA synthesis
• D)Decreased activity of bacterial catalase-peroxidase
• E)Increased activity of enzymes involved in cell wall polysaccharide synthesis

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Definitions:

Heart Disease

A range of conditions that affect the heart, including coronary artery disease, arrhythmias, and congenital heart defects.

Anti-Inflammatory Drugs

Medications designed to reduce inflammation and relieve pain; includes both over-the-counter and prescription drugs.

CVD

Stands for Cardiovascular Disease, encompassing a range of heart and blood vessel conditions, including coronary artery disease and stroke.

Inflammation

The body's protective response to injury or damage, characterized by redness, swelling, heat, and sometimes pain and loss of function.