A 54-Year-Old Man with HIV Is Part of a Large

question 34

Multiple Choice

A 54-year-old man with HIV is part of a large clinical study.  He was diagnosed with HIV-1 infection 5 years ago.  Blood samples are obtained periodically to perform sequencing analysis of the viral genome.  Current testing reveals a large number of isolates with mutation in the pol gene compared to the previous analyses.  This finding is most closely associated with which of the following?

• A)Evasion of humoral immune response
• B)Inconsistent use of antiretroviral therapy
• C)Ineffective CD8 cytotoxicity
• D)Prevention of CD4 cell apoptosis
• E)Reduction of viral replication

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Definitions:

P(A and B)

The probability that both events A and B occur.

P(A)

The probability of event A occurring, an elementary concept in probability and statistics.

P(B)

The likelihood that event B will happen.

Drunk Drivers

Individuals who operate a vehicle while under the influence of alcohol, significantly increasing the risk of accidents and impairments in judgement and coordination.