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A 64-Year-Old Man Has Had Difficulty Walking for 6 Months

question 688

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A 64-year-old man has had difficulty walking for 6 months, experiencing muscle cramps in his right thigh after walking a block on level ground.  The cramps subside quickly with rest.  He has also had decreased sexual performance.  Medical history is significant for hypercholesterolemia and myocardial infarction.  The patient smokes a pack of cigarettes daily but does not use alcohol or illicit drugs.  He is afebrile.  Blood pressure is 128/78 mm Hg, pulse is 76/min, and respirations are 16/min.  Cardiac auscultation reveals normal S1 and S2, and equal vesicular breath sounds are heard over the bilateral lungs.  The abdomen is soft and without masses.  There is no peripheral edema, muscle tenderness, or muscle weakness.  Which of the following is the most likely cause of this patient's symptoms?


Definitions:

Securities' Returns

The profit or loss generated on a security over a particular period, usually expressed as a percentage.

Variances

The quantitative measure of the difference between actual and expected behavior, often used in finance to assess volatility of returns or tracking errors.

Covariances

An indicator of the extent to which two variables fluctuate in tandem.

Risky Securities

Financial instruments carrying a higher potential for loss, often offering greater potential returns to compensate for the increased risk.

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