A 26-Year-Old Woman Is Evaluated for Intermittent Abdominal Discomfort, Diarrhea

question 204

Multiple Choice

A 26-year-old woman is evaluated for intermittent abdominal discomfort, diarrhea, and melena.  The patient undergoes colonoscopy followed by total colectomy due to significant colonic abnormalities.  Representative colon findings are shown in the image below. Her sister, who has the same biological parents and has no symptoms, also undergoes screening colonoscopy and has similar findings.  If left untreated, which of the following is the most likely lifetime risk of colon cancer in the patient's sister?

• A)About 25%
• B)About 50%
• C)About 75%
• D)Close to 100%
• E)Same as general population

---

Definitions:

Normal Model

A statistical representation of a normal distribution, where data is symmetrically distributed around the mean.

Mean Speed

The average rate at which an object covers distance, calculated by dividing the total distance by the total time taken.

Normal Model

A statistical representation of data sets depicting their distribution typically assumed to be Gaussian or bell-shaped.

Unusually Low

Values or observations that significantly deviate below the expected range within a dataset or statistical analysis.