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A 70-year-old man comes to the office due to persistent epigastric discomfort and nausea for the past several months. He has also noticed black-colored stools on several occasions. Medical history is notable for hypertension and osteoarthritis. The patient emigrated from rural China 5 years ago to live with his daughter. He does not use tobacco, alcohol, or illicit drugs. Physical examination shows a thin male with pale mucous membranes, an enlarged left supraclavicular lymph node, and epigastric tenderness on deep palpation. Stool testing for occult blood is positive. Upper gastrointestinal endoscopy reveals a 3-cm ulceration at the gastric antrum, with a heaped-up irregular border. Biopsy from the edge of the ulcer reveals glandular structures containing intestinal-like columnar cells. Which of the following most likely predisposed this patient to his current condition?
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A business or property ownership arrangement where two or more parties hold a share or interest.
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