A 53-Year-Old Man Comes to the Physician Due to Frequent

question 172

Multiple Choice

A 53-year-old man comes to the physician due to frequent headaches and dizziness.  He has a history of hypertension and peptic ulcer disease.  His medications include daily chlorthalidone and antacids as needed.  The patient's temperature is 37 C (98.6 F) , blood pressure is 146/92 mm Hg, pulse is 89/min, and respirations are 16/min.  His BMI is 26 kg/m².  Physical examination shows facial plethora and moderate splenomegaly.  Laboratory results are as follows: This patient most likely has a mutation in which of the following types of proteins?

• A)Cytoplasmic tyrosine kinase
• B)Growth-stimulating transcription factor
• C)Intrinsic receptor tyrosine kinase
• D)Tumor suppressor protein
• E)Vascular growth factor

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Definitions:

Psychosurgery

Surgical operations on the brain intended to relieve severe mental disorders or alter behavior and mood.

Removing Brain Tissue

A surgical procedure that involves the excision of part of the brain to treat neurological or psychological disorders.

Electric Current

The flow of electric charge through a conductor, typically measured in amperes.

Antidepressant Drugs

Medications used to treat depression by influencing neurotransmitter levels in the brain.