A 24-Year-Old Man Comes to the Physician with Complaints of Tinnitus

question 763

Multiple Choice

A 24-year-old man comes to the physician with complaints of tinnitus, vertigo, and hearing loss.  A contrast-enhanced, T1-weighted image of his brain is shown below. This patient's condition is most likely associated with a mutation involving which of the following genes?

• A)APC on chromosome 5
• B)NF1 on chromosome 17
• C)NF2 on chromosome 22
• D)p53 on chromosome 17
• E)RB1 on chromosome 13
• F)VHL on chromosome 3

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