An 18-Year-Old Man Is Evaluated Due to 3 Months of Lower

question 279

Multiple Choice

An 18-year-old man is evaluated due to 3 months of lower extremity pain.  The pain is persistent and present both day and night.  He has no fever, chills, or history of leg trauma.  Imaging shows an expansile lesion of the distal femur.  Surgical resection is performed, and the specimen is shown below. Mutations involving which of the following genes are most likely present in this patient?

• A)BRAF
• B)HER2
• C)KRAS
• D)RB1
• E)RET

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Definitions:

Competing Preferences

involves situations where individuals face choices between options that cannot be reconciled, often requiring prioritization based on values or desired outcomes.

Peer Influence

The effect that the attitudes, behaviors, and actions of individuals within a group have on each other, typically seen in social and developmental contexts.

Health-Promotion Plan

A structured approach to improving the health and well-being of individuals or communities through education, lifestyle adjustments, and preventative measures.

Rehabilitation Unit

A specialized department in a hospital or healthcare facility dedicated to providing intensive therapy services to help patients recover and regain function after illness, surgery, or injury.