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A 32-Year-Old Man Comes to the Office Due to Intermittent

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A 32-year-old man comes to the office due to intermittent dysphagia for solids and liquids.  He has no significant past medical history and does not use tobacco, alcohol, or illicit drugs.  His father has a history of esophageal squamous cell carcinoma.  Physical examination is unremarkable.  The patient undergoes an esophageal manometric study that demonstrates periodic, simultaneous, and non-peristaltic contractions of large amplitude and long duration.  Which of the following is the most likely pathogenesis of this patient's esophageal condition?


Definitions:

Price Competition

A type of competition in which companies try to attract customers by offering lower prices than their competitors.

Equilibrium Payoff

In game theory, the reward or outcome each player expects to receive when all players choose strategies that lead to a stable state where no player can benefit by changing their strategy alone.

Advertising Strategy

An advertising strategy is a plan designed to reach and persuade potential customers to buy a product or service or take any action desired by the advertiser.

Nash Equilibrium

A concept in game theory where players reach an outcome from which no player can benefit by unilaterally changing their strategy.

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