A 34-Year-Old Man Is Evaluated for Elevated Liver Aminotransferases

question 157

Multiple Choice

A 34-year-old man is evaluated for elevated liver aminotransferases.  The patient has no chronic medical conditions but has a history of injection drug use.  Family history is notable for liver cirrhosis in his mother.  Ultrasonography-guided liver biopsy is performed.  Histopathology demonstrates marked panlobular mononuclear cell infiltration that cross into adjacent lobules.  Occasional intensely eosinophilic round bodies are seen scattered amongst the hepatic parenchyma.  Which of the following is the most likely cause of the latter histopathological finding in this patient?

• A)Coagulative necrosis due to a toxin
• B)Cytotoxic T-cell-mediated apoptosis
• C)Intracellular pigment accumulation
• D)Intracytoplasmic cytokeratin deposition
• E)Small foci of fibrinoid necrosis
• F)Stellate cell activation into myofibroblast

---

Definitions:

Present Value

Present value is a financial concept that calculates the current worth of a future sum of money or stream of cash flows, given a specified rate of return.

Annuity

A financial product that pays out a fixed stream of payments to an individual, often used as an investment for retirement.

Earnings Rate

A measure of the profitability of a company or investment, typically expressed as a percentage.

Net Present Values

A method used in capital budgeting to analyze the profitability of an investment or project by calculating the present values of all cash inflows and outflows.