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A 15-year-old boy comes to the office for a follow-up appointment. Since early childhood, he has suffered from recurrent respiratory infections and chronic diarrhea. The patient has been hospitalized several times for parenteral antibiotic treatment. Current prescribed medications include pancreatic enzyme therapy and a number of dietary supplements. Physical examination shows decreased proprioception and hyporeflexia in the lower extremities. Laboratory findings are suggestive of mild hemolytic anemia. Which of the following conditions is the most likely cause of these findings?
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