A 3-Year-Old Boy Is Being Evaluated for Recurrent Generalized Seizures

question 649

Multiple Choice

A 3-year-old boy is being evaluated for recurrent generalized seizures and developmental delay.  Physical examination is notable for scattered hypopigmented skin patches.  MRI of the head reveals multiple masses, most of which line the ependymal surfaces of the lateral ventricles, and some are calcified, as shown in the below image. Which of the following is the most likely underlying cause of this patient's brain lesions?

• A)Benign hamartoma formation
• B)Lysosomal metabolite accumulation
• C)Malignant lymphoid proliferation
• D)Mycobacterial meningeal invasion
• E)Tapeworm larvae migration

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Definitions:

Error Term

A variable in statistical models that represents the difference between the observed and predicted values, accounting for randomness or unexplained variation.

Independent

Describes variables in an experiment or study that are manipulated or categorized separately from any other variables.

Normally Distributed

Describes a statistical distribution that is symmetric about the mean, showing that data near the mean are more frequent in occurrence than data far from the mean.

Mathematical Equation

A statement of equality between two expressions which holds true under certain conditions.