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A 27-Year-Old Man Comes to the Emergency Department with Progressive

question 474

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A 27-year-old man comes to the emergency department with progressive right knee swelling and pain.  He has no history of trauma to the area.  The patient has no other medical conditions and takes no medications.  X-rays reveal a large lytic lesion involving the proximal tibia with extensive soft-tissue swelling.  After additional confirmatory testing, the patient undergoes a right-sided, above-knee amputation.  Histologic examination of the resected mass is shown in the exhibits.  A 27-year-old man comes to the emergency department with progressive right knee swelling and pain.  He has no history of trauma to the area.  The patient has no other medical conditions and takes no medications.  X-rays reveal a large lytic lesion involving the proximal tibia with extensive soft-tissue swelling.  After additional confirmatory testing, the patient undergoes a right-sided, above-knee amputation.  Histologic examination of the resected mass is shown in the exhibits.      Which of the following is the most likely diagnosis? A) Chondrosarcoma B) Ewing sarcoma C) Metastatic adenocarcinoma D) Osteoid osteoma E) Osteosarcoma
A 27-year-old man comes to the emergency department with progressive right knee swelling and pain.  He has no history of trauma to the area.  The patient has no other medical conditions and takes no medications.  X-rays reveal a large lytic lesion involving the proximal tibia with extensive soft-tissue swelling.  After additional confirmatory testing, the patient undergoes a right-sided, above-knee amputation.  Histologic examination of the resected mass is shown in the exhibits.      Which of the following is the most likely diagnosis? A) Chondrosarcoma B) Ewing sarcoma C) Metastatic adenocarcinoma D) Osteoid osteoma E) Osteosarcoma
Which of the following is the most likely diagnosis?


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