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A 45-Year-Old Man Comes to the Office for Evaluation of Fatigue

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A 45-year-old man comes to the office for evaluation of fatigue that has been gradually increasing over the past 4 months.  The patient has had difficulty keeping up with the labor involved with his job as a construction worker.  Over the past 2 weeks, he has been unable to climb past the second floor of the building his company is renovating.  The patient also has increasing shortness of breath with minor activities, such as lifting his toolbox out of the car.  Review of systems reveals constipation and decreased concentration.  Physical examination shows an overweight male with conjunctival pallor who has difficulty getting onto the examination table due to shortness of breath.  Laboratory test results are as follows: A 45-year-old man comes to the office for evaluation of fatigue that has been gradually increasing over the past 4 months.  The patient has had difficulty keeping up with the labor involved with his job as a construction worker.  Over the past 2 weeks, he has been unable to climb past the second floor of the building his company is renovating.  The patient also has increasing shortness of breath with minor activities, such as lifting his toolbox out of the car.  Review of systems reveals constipation and decreased concentration.  Physical examination shows an overweight male with conjunctival pallor who has difficulty getting onto the examination table due to shortness of breath.  Laboratory test results are as follows:   Which of the following findings would most likely be seen on this patient's peripheral blood smear? A) Basophilic stippling B) Heinz bodies C) Howell-Jolly bodies D) Ring sideroblasts E) Schistocytes Which of the following findings would most likely be seen on this patient's peripheral blood smear?


Definitions:

Renaissance Ideas

Concepts and philosophical foundations of the Renaissance, a period of rebirth in arts, culture, and intellectual pursuits, emphasizing humanism, individualism, and rediscovery of classical antiquity.

International Style

A style of 20th-century architecture associated with Le Corbusier, whose elegance of design came to influence the look of modern office buildings and skyscrapers.

Foreshortening

A technique used in perspective to create the illusion of an object receding strongly into the distance or background.

International Gothic

A style of 14th- and 15th-century painting begun by Simone Martini, who fused the French Gothic manner with Sienese art. This style appealed to the aristocracy because of its brilliant color, lavish costumes, intricate ornamentation, and themes involving splendid processions of knights and ladies.

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