A Newborn Is Being Evaluated in the Nursery

question 272

Multiple Choice

A newborn is being evaluated in the nursery.  The patient was born at term via spontaneous vaginal delivery to a 23-year-old woman.  The mother developed dark terminal facial hair and a deepened voice during the pregnancy.  The delivery was unremarkable, and the patient's vital signs are within normal limits.  Examination shows ambiguous genitalia and clitoromegaly.  Laboratory studies reveal elevated serum levels of testosterone and androstenedione.  Karyotype testing shows a 46,XX genotype.  Ultrasound of the pelvis shows a normal-sized uterus.  This infant's presentation is most likely due to deficiency of which of the following enzymes?

• A)5-Alpha reductase
• B)17-Alpha hydroxylase
• C)21-Hydroxylase
• D)Aromatase
• E)HMG-CoA reductase

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Definitions:

Inventory

All products and materials that a company holds, aimed at either resale or being incorporated into manufacturing processes.

FOB Shipping Point

A term of sale indicating that the buyer assumes responsibility for shipping costs and risk of loss once the seller has delivered the goods to the shipping carrier.

Sales Discount

A reduction in the price of a product or service offered to customers, typically to prompt early payment or bulk purchases.

Cash Returns

Financial returns or profits that are received in the form of cash, as opposed to stock dividends or other non-liquid forms of return.