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A 44-Year-Old Man Reports Exertional Shortness of Breath and Palpitations

question 472

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A 44-year-old man reports exertional shortness of breath and palpitations.  On examination, he has a systolic murmur at the left sternal border and cardiac apex, which gets louder when he stands up.  He is diagnosed with obstructive hypertrophic cardiomyopathy and paroxysmal atrial fibrillation, and is started on a medication.  Changes in the action potential of ventricular muscle cells before and after administration of medication are shown in the image below A 44-year-old man reports exertional shortness of breath and palpitations.  On examination, he has a systolic murmur at the left sternal border and cardiac apex, which gets louder when he stands up.  He is diagnosed with obstructive hypertrophic cardiomyopathy and paroxysmal atrial fibrillation, and is started on a medication.  Changes in the action potential of ventricular muscle cells before and after administration of medication are shown in the image below   Black curve = Before administration of medication Red curve = After administration of medicationThe patient is most likely being treated with which of the following medications? A) Adenosine B) Digoxin C) Diltiazem D) Disopyramide E) Flecainide F) Lidocaine G) Propranolol Black curve = Before administration of medication
Red curve = After administration of medicationThe patient is most likely being treated with which of the following medications?


Definitions:

BMI

Body Mass Index, a numerical value calculated from a person's weight and height, used to evaluate if a person is underweight, normal weight, overweight, or obese.

A&P

Anatomy and Physiology, the scientific disciplines that study the structure and function of the body.

Anatomy

The branch of biology concerned with the study of the structure of organisms and their parts.

Physiology

The branch of biology that deals with the functions and activities of living organisms and their parts, including all physical and chemical processes.

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