A 12-Year-Old Boy Is Brought to the Emergency Department Due

question 278

Multiple Choice

A 12-year-old boy is brought to the emergency department due to a skin infection.  Temperature is 38.4 C (101.1 F) .  Physical examination shows an area of erythema, warmth, and tenderness on his right distal leg.  Laboratory results are notable for leukocytosis.  The patient is started on intravenous nafcillin.  Two days later, he shows limited response to antibiotic therapy.  Light microscopy of pus obtained from the site shows gram-positive cocci in clusters, and sensitivity testing demonstrates little response to nafcillin but good response to vancomycin.  Which of the following is the most likely explanation for nafcillin treatment failure in this patient?

• A)Active drug transport out of the cell
• B)Enzymatic degradation of the drug
• C)Mutation in DNA gyrase
• D)Mutation in RNA polymerase
• E)Poor interaction with binding proteins

Understand the limitations and accuracy of expert predictions in world politics.

Recognize the concept of functional fixedness and its effects on problem-solving.

Identify circumstances under which individuals are most likely to take risks.

Understand how experience and context can impact perception and identification tasks.

---

Definitions:

Noncommunicable Disease

A disease that cannot be transmitted from one person to another, often chronic in nature, such as heart disease or diabetes.

Communicable Disease

An illness caused by specific infectious agents or their toxic products, which can be transmitted from person to person.

Spiritual Wellness

A sense of purpose and meaning in life, reflecting an individual’s values, beliefs, and practices.

Emotional Wellness

The capability to effectively manage the pressures of life and adjust to changes and challenging periods.