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A 62-Year-Old Man Comes to the Office for Follow-Up

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A 62-year-old man comes to the office for follow-up.  The patient has a 10-year history of type 2 diabetes mellitus.  Over the past 2 years, he has had burning pain and pins and needle sensations in his feet, which is worse at nighttime.  Nortriptyline was prescribed, and the dosage was gradually increased.  Currently, the patient takes the maximal recommended dose but states the symptoms are not well controlled.  He reports no drug adverse effects.  Other medical history includes hypertension and hyperlipidemia.  Blood pressure is 124/70 mm Hg and pulse is 68/min.  Physical examination shows decreased light touch and pain sensation in the feet.  Ankle reflexes are decreased bilaterally.  His most recent hemoglobin A1c level is 7.0%.  Appropriate foot care is advised, and additional pharmacotherapy for the patient's symptoms is planned.  Which of the following medications would provide additional benefit through a different mechanism with no drug-drug interaction?

Consider power as a dynamic and double-edged concept that has both positive and negative effects on organizations and individuals.
Understand the concept and different sources or bases of power.
Recognize Bertrand Russell's perspective on the formalization of power.
Distinguish between overt and covert power.

Definitions:

Equal Distribution

The concept of distributing resources or income in a way that every member of a society gets an equal share.

Marginal Cost

The expense incurred from the manufacture of an extra single unit of a product or service.

Opportunity Cost

The expense incurred from not choosing the second-best option available during decision-making.

Marginal Cost

The swell in aggregate expenditure due to the production of an additional unit of a product or service.

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