A 25-Year-Old Man Is Brought to the Emergency Department After

question 400

Multiple Choice

A 25-year-old man is brought to the emergency department after being found unresponsive.  He has a history of schizoaffective disorder and previous suicide attempts by prescription medication overdose.  The patient was recently started on haloperidol and sertraline.  Temperature is 40.6 C (105 F) , blood pressure is 180/98 mm Hg, and pulse is 112/min.  On examination, the patient is obtunded and diffusely rigid without clonus.  Laboratory studies show serum creatinine of 3.2 mg/dL, creatine kinase of 75,000 U/L, and leukocytes of 16,000/mm³.  The antidote for this patient's current condition most likely has which of the following mechanisms of action?

• A)Activation of presynaptic voltage-gated calcium channels of motor neurons
• B)Antagonism of peripheral and central serotonin receptors
• C)Blockade of central dopamine D2 receptors
• D)Inhibition of acetylcholinesterase at the neuromuscular junction
• E)Inhibition of calcium ion release from sarcoplasmic reticulum of skeletal muscle

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Definitions:

Dominant Culture

The prevailing culture in a given society, which often sets norms, values, and practices that are widely adopted or enforced.

Constructive Play

Play in which children manipulate objects to produce or build something.

Functional Play

Play that involves simple, repetitive activities typical of three-year-olds.

Parallel Play

Action in which children play with similar toys, in a similar manner, but do not interact with each other.