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A Group of Investigators Is Performing an Experiment Designed to Assess

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A group of investigators is performing an experiment designed to assess genetic variability in drug biotransformation.  A fixed dose of isoniazid is given to a group of volunteers, and the plasma drug concentration is measured four hours following administration of the drug.  The following distribution of plasma drug concentration in these subjects is obtained. A group of investigators is performing an experiment designed to assess genetic variability in drug biotransformation.  A fixed dose of isoniazid is given to a group of volunteers, and the plasma drug concentration is measured four hours following administration of the drug.  The following distribution of plasma drug concentration in these subjects is obtained.   Variation of which of the following processes provides the best explanation for the shaded area of the curve? A) Methylation B) Glucuronidation C) Hydrolysis D) Acetylation E) Amine oxidation Variation of which of the following processes provides the best explanation for the shaded area of the curve?


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