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A 46-Year-Old Man Comes to the Emergency Department with Flank

question 120

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A 46-year-old man comes to the emergency department with flank pain and hematuria.  The pain is similar to several previous episodes of kidney stones.  Abdominal imaging reveals a radiopaque calculus in the right ureter.  The patient is admitted to the hospital and given intravenous hydration and analgesics.  He subsequently passes the stone with rapid relief of his symptoms.  Chemical analysis reveals that the stone is composed primarily of calcium oxalate.  Which of the following medications is most likely to prevent recurrent stone formation in this patient?


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